Superantigen insert found in the spike of SARS-2

It's about a superantigen insert in the spike of SARS-2 that isn't in the spike of SARS.

 

Jessica Rose

Jul 13

This Substack is about another danger associated with the spike protein, and not just the viral spike. This danger is called a superantigen. A superantigen can activate all sorts of T cells non-specifically to induce hyperinflammation and cytokine storms, for example.

A beautiful paper is currently uploaded to the pre-print server OSF PREPRINTS (submitted in November 2021) entitled: “Differences in Vaccine and SARS-CoV-2 Replication Derived mRNA: Implications for Cell Biology and Future Disease”.1 This paper looks at the differences between SARS-nCoV-2 viral spike and the modified mRNA injection spike and asks the question: is the modified spike as, even more pathogenic, than the SARS spike? Basically.

The authors rightly point out in the conclusion that transparency and quality control are necessary aspects of any biological roll out into humans. They penned an extremely well-researched and articulated paper based on the potential devastating effects of codon optimization of the spike protein currently being injected into everyone, but that they are not able to publish it. For some reason. The ‘reasons’ being given to them sound very familiar to the ‘reason’ that Peter and I received in the context of our Myocarditis paper that is still in limbo.

Public and transparent quality control of these often-mandated injections are required. This should include sequence verification and quality control of the various lots and evidence of the proteins these mRNA express in patients.

Another very interesting topic of concern raised in this paper is the following: there is a superantigen residing in the SARS-nCoV-2 spike protein. Was it put there? Before I proceed into this Substack further, I highly recommend reading Kevin, Peter and Anthony’s paper and if you’re interested, Tamara Ugolini interviewed Kevin on this subject matter recently and you can watch that here.

The paper I would like to Substack today is one in their reference list entitled: “Superantigenic character of an insert unique to SARS-CoV-2 spike supported by skewed TCR repertoire in patients with hyperinflammation”.2 The title really says it all. There’s a superantigen in the spike protein and it was inserted.

I find it hard to believe that I only found this paper today. Everyone should be talking about this. What they show is that there is a short sequence of amino acids (epitope) in the SARS-nCoV-2 spike protein that potentially mediates high-affinity, non-specific binding to the T Cell Receptor (TCR) to induce massive non-specific activation of the immune system - cytokine storms and such leading to things like death. This short sequence represents a sequence found in Staphylococcal enterotoxin B (SEB)3 and is called a superantigen due to the above-mentioned properties.

Figure 1: Schematic of activation of TCR by antigen, and by superantigen. https://www.slideshare.net/MUBOSScz/immunology-vii-hlaregulation

For the rest of this article please go to source link below.

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(Source: jessicar.substack.com; July 13, 2022; https://tinyurl.com/26sppc4q)
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