The psychedelic that makes mice live 60 percent longer could be the key to human longevity as well

Why the same mushroom that expands your mind also extends your cellular lifespan

In 1971, the U.S. government classified psilocybin as having "no accepted medical use." In 2025, scientists discovered it could extend human cellular lifespan by 57%.

What if the greatest longevity breakthrough of our time has been growing in cow pastures all along?

For decades, psilocybin—the active compound in "magic" mushrooms—was dismissed as a counterculture relic, criminalized and forgotten by mainstream medicine. Yet groundbreaking research now reveals something extraordinary: this ancient fungal ally doesn't just heal minds and souls—it appears to slow biological aging itself, protecting DNA, extending cellular lifespan, and potentially adding years to human life.

This isn't another wellness trend. This is hard science catching up to what indigenous healers, mystics, and visionaries like Terence McKenna have insisted for decades: psilocybin isn't just a drug—it's a teacher, a survival tool, and perhaps one of evolution's greatest gifts to human longevity.

From Underground Sacrament to Breakthrough Medicine

The transformation has been nothing short of remarkable. What was once whispered about at Grateful Dead shows is now studied in the halls of Harvard, Johns Hopkins, and Emory University. Over 170 clinical studies have documented psilocybin's therapeutic potential across an astonishing spectrum of conditions¹:

Mental Health Revolution:

  • Treatment-resistant depression (with FDA "Breakthrough Therapy" designation) - Read the recent GreenMedInfo report here.

  • Anxiety, PTSD, and end-of-life existential distress

  • Addiction recovery for alcohol, tobacco, and other substances

Neurological Frontiers:

  • Alzheimer's and Parkinson's disease

  • Cluster headaches, chronic pain, and traumatic brain injury recovery

Beyond the Brain:

  • Immune system modulation

  • Chronic inflammatory conditions

  • And now—biological aging itself

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By Sayer Ji / Founder of Greenmedinfo.com

Sayer Ji is founder of Greenmedinfo.com, a reviewer at the International Journal of Human Nutrition and Functional Medicine, Co-founder and CEO of Systome Biomed, Vice Chairman of the Board of the National Health Federation, Steering Committee Member of the Global Non-GMO Foundation.

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(Source: substack.com; August 15, 2025; https://tinyurl.com/2whzymzc)
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